Bukayo Saka has netted 12 goals in 44 caps for the national team.
England have included Bukayo Saka for upcoming fixtures versus Latvia and Wales, however no room for Bellingham, Phil Foden or Grealish.
Arsenal forward Bukayo Saka missed the previous World Cup qualifying successes over Serbia and Andorra with a hamstring issue.
Saka recently returned for Arsenal and found the net in their victory against Olympiacos on Wednesday.
Saka comes in for club colleague Noni Madueke, who is sidelined till next month with a knee problem.
The Three Lions face the Welsh in a warm-up match at Wembley on Thursday prior to a qualifying match in Riga on October 14.
Should England triumph against Latvia, they will need a just two more points from their final two qualifiers against Serbia and Albania in November to qualify for the World Cup in North America.
Leverkusen's Quansah replaces Newcastle United’s Tino Livramento, who is out for up to eight weeks following suffering a knee issue versus Arsenal recently.
Elliot Anderson and Djed Spence, who received their maiden national team selections previously, keep their spots. Loftus-Cheek also keeps his spot, even with the recovery of Adam Wharton.
Saka has featured in just one game for Tuchel since he became national team boss, because of fitness and hamstring injuries.
Bellingham missed the previous squad as he recovered from a shoulder operation and has only made a single start for Real Madrid after coming back from injury.
Foden was left out from the coach’s last England squad following a loss of form and has been unable to force his way back, despite a strong start to the campaign with Manchester City.
Grealish also is excluded in spite of a revival in form on loan at Everton. He has not featured for the national team since last year.
Complete England Selection
Goalkeepers: Dean Henderson (Palace), Jordan Pickford (Everton), Trafford (Manchester City)
Backline: Burn (Newcastle), Guehi (Crystal Palace), James (the Blues), Ezri Konsa (Villa), Myles Lewis-Skelly (the Gunners), Jarell Quansah (Bayer Leverkusen), Djed Spence (Tottenham Hotspur), Stones (Manchester City)
Midfielders: Anderson (Nottingham Forest), Gibbs-White (Forest), Jordan Henderson (the Bees), Loftus-Cheek (Milan), Rice (the Gunners), Morgan Rogers (Aston Villa)
Attackers: Jarrod Bowen (West Ham), Eze (Arsenal), Gordon (Newcastle), Kane (Bayern Munich), Marcus Rashford (Barcelona), Saka (the Gunners), Watkins (Aston Villa)
'Focus on omissions over inclusions'
Thomas Tuchel's latest England squad brings scrutiny on those the head coach has omitted rather than the players he has selected.
Bellingham’s exclusion may cause surprise but the coach understandably feels there is no need to recall the Madrid midfielder.
Manchester City's Foden and loanee Grealish have both excelled at the start of the season.
Those who Tuchel utilised in England's qualifying victories against Serbia and Andorra deserve the reward of continuity.
There will be regret that Arsenal's Noni Madueke is not included because of a fitness issue.
Anderson has settled well at England senior level.
The England boss is a fan of Grealish, especially, as well as Foden.
If there is one surprise, it comes in the exclusion of Crystal Palace midfielder Adam Wharton.
Bellingham, naturally, will be needed further down the line.
